A Cal 500
| Company | Acme Laboratories Ltd. | |
|---|---|---|
| Active Ingredient |  Calcium Carbonate | |
| Variants |
| |
Dose
Adult: PO Hyperacidity: Take 1-2 tab as needed, up to a max of 16 tab/day. May suck or chew tablets.
Hyperphosphataemia in chronic renal failure Initial: 2.5 g/day, up to 17 g/day in divided doses.
Renal impairment:
CrCl (ml/min)
<25 Dosage adjustments may be needed depending on serum calcium levels.
Alternative Brands to A Cal 500
- Acical
- Acical 500
- Acical Jr.
- A Cal Chewable 250
- Kidcal
- Kidcal 250
- A-Cal 250
- Calcium A
- Ostocurb 500
- Boncal
- Calcium (Chewable)
- Calcium DS
- Calcarb 500
- Ambeecal
- Oracal 500
- Apocal 500
- Apocal Chewable 250
- Calfeed
- Calbon 500
- Caljuven Chewable 250
- Calfor
- Protebon 500
- Cinet
- Carben 500
- Aristocal 500
- Orthocal 500
- Bpcal 500
- Cenet
- Calciton 500
- Monocal
- Suplecal 500
- Cpcal 500
- Boni 500
- Canta
- Ostoplus 500
- Isocal 500
- Caldil
- Caldil 500
- Edical 500
- Ostocal 500
- Ostocal Family
- Ostocal JR 250
- Tumy 250
- Eurocal
- Evecal 500
- Calcifil
- Costin 250MG
- Costin 500
- Carbocal 500
- Caltonic
- Ostim 500
- Rocal 500
- Calmax 250
- Ipical 500
- Calcicar 250
- Calcicar 500
- Indocal 500
- Jasocal 250
- Jasocal 500
- Casalt 500
- Ossi 500
- Bonacal 500
- Calpo 500
- Med Cal 500
- Cabonate 500
- Calos 500
- Calsto 500
- Mystocal
- Calcium-500
- Calcium-J
- Miracal J
- Miracal-500
- Myocal
- Starcal
- Calcium Sandoz 250
- Calsan
- Sandocal 500
- Rejuven 500
- Maxcal
- Ostogen
- Mycal
- Bonec 500
- Cal 250
- Cal 500
- Peocal 500
- Calium-500
- Xtracal
- Precal
- Sancal
- Ostacid 500
- Calcin 500
- Calci-D
- Saltonate 500
- See-Cal 500
- Procala 500
- Calcibost
- Silcal
- Calsil 500
- Calmet 500
- Cal Up
- Calbo JR 250
- Calbo-D
- Calboral-D
- Sucal 500
- Sycal 500
- Oscal 500
- Neocal 500
- Calcizen DS
- Caldical 500
- Onecal
Indication
Heartburn, Indigestion, Calcium deficiency, Hypocalcaemia, Hyperphosphatemia, Calcium supplement, Stomach upset
Contra Indication
Patients with Ca renal calculi or history of renal calculi; hypercalcaemia; hypophosphataemia. Patients with suspected digoxin toxicity.
Side Effect
Constipation, flatulence; hypercalcaemia; metabolic alkalosis; milk-alkali syndrome, tissue-calcification. Gastric hypersecretion and acid rebound (with prolonged use).
Interaction
Co-administration with thiazide diuretics or vit D may lead to milk-alkali syndrome and hypercalcaemia. Decreased absorption with corticosteroids. Decreases absorption of tetracyclines, atenolol, iron, quinolones, alendronate, Na fluoride, Zn and calcium-channel blockers. Enhances cardiac effects of digitalis glycosides and may precipitate digitalis intoxication.
Therapeutic Classes
- Specific mineral preparations
- Minerals in bone formation
Indicaitons
- Heartburn
- Indigestion
- Calcium deficiency
- Hypocalcaemia
- Stomach upset
- Pseudohypoparathyroidism
- Non ulcer dyspepsia
- Hyperphosphataemia
Precaution
Renal impairment, hypoparathyroid disease, hypercalcaemia-associated diseases. Calcium absorption is impaired in achlorhydria; use an alternate salt and take with food. Caution when used in patients with a history of kidney stones.
Mode of Action
Calcium carbonate can neutralise gastric acid rapidly and effectively. However, it may adversely activate Ca dependent processes, leading to secretion of gastric and hydrochloric acid. It can induce rebound acid secretion and, prolonged high doses may cause hypercalcemia, alkalosis and milk-alkali syndrome.