|Company||Ambee Pharmaceuticals Ltd.|
Adult: PO 150 mg twice daily or 300 mg once daily for 5-10 days.
Paediatric dose: The dose for children is 2.5 to 5 mg/kg body weight twice a day.
Alternative Brands to A Rox
Pneumonia, Pharyngitis, Susceptible infections, Sinusitis, Otitis media, Cellulitis,Tonsillitis, Folliculitis, Carbuncles, Prostatitis, Urethritis, Acute and chronic bronchitis, Bronchopneumonia, Furuncles, Pyoderma, Impetigo and infected dermatitis, Cervicitis and salpingitis
Nausea, vomiting, abdominal pain, diarrhoea, weakness, malaise, anorexia, constipation, dyspepsia, flatulence; hepatitis; rashes, headache, dizziness, weakness, changes in blood counts; increased liver enzyme values; eosinophilia; rarely, acute pancreatitis.
May raise serum levels of ciclosporin and digoxin. Increased risk of rhabdomyolysis when used with simvastatin.
- Susceptible infections
- Otitis media
- Impetigo and infected dermatitis
- Cervicitis and salpingitis
Hepatic impairment. Monitor liver function. Prolonged treatment increases risk of hepatotoxicity. History of arrhythmias.
Mode of Action
Roxithromycin inhibits protein synthesis by irreversibly binding to the 50s ribosomal subunits thus blocking the transpeptidation or translocation reactions of susceptible organisms resulting in stunted cell growth.