A Tetra 1%
|Company||Acme Laboratories Ltd.|
|Active Ingredient||Tetracycline Hydrochloride 1% Eye prep|
Adult & Child: Apply 2 hourly in acute eye infection.
Alternative Brands to A Tetra 1%
Bacterial Conjunctivitis, trachoma.
Hypersensitivity; pregnancy, lactation, children; renal impairment.
Burning, irritation, visual disturbances, superinfections, photosensitivity, hypersensitivity,
Impaired absorption w/ antacids containing divalent and trivalent cations (e.g. Al, Ca, Mg), Fe, Zn and Na bicarbonate preparations, kaolin-pectin, bismuth subsalicylate, sucralfate, strontium ranelate, colestipol and colestyramine. May interfere w/ the bactericidal action of penicillin. May potentiate the effect of anticoagulants. May decrease efficacy of oral contraceptives. Nephrotoxic effects may be exacerbated by diuretics or other nephrotoxic drugs. May increase the hypoglycaemic effect of insulin and sulfonylureas in patients w/ DM. May increase toxic effects of ergot alkaloids and methotrexate.
Potentially Fatal: Concurrent methoxyflurane may result to fatal renal toxicity. Increased risk of benign intracranial HTN w/ vit A or retinoids (e.g. acitretin,isotretinoin, tretinoin).
- Ophthalmic Anti-bacterial products
- Bacterial Conjunctivitis
- Bacterial eye infections
Hepatic impairment. Avoid exposure to sunlight. Periodic evaluation of renal, hepatic and haematological system during prolonged therapy.
Mode of Action
Tetracycline exhibits its bacteriostatic action by reversibly binding to the 30S subunits of the ribosome, thus preventing protein synthesis and arresting cell growth. It has a broad spectrum of antimicrobial activity including Chlamydiaceae, Mycoplasma spp., Rickettsia spp., spirochaetes, many aerobic and anaerobic gm+ve and gm-ve pathogenic bacteria and some protozoa.