A Zyme
| Company | Acme Laboratories Ltd. | |
|---|---|---|
| Active Ingredient |  Pancreatin | |
| Variants |
| |
Dose
Adult: PO 1-3 tablets daily with meal.
Alternative Brands to A Zyme
Indication
Pancreatic insufficiency
Contra Indication
Acute pancreatitis or acute exacerbation of chronic pancreatic disease.
Side Effect
GI effects e.g. abdominal discomfort, nausea and vomiting. Buccal and perianal irritation, particularly in infants. Colonic strictures may occur, mainly in children with cystic fibrosis receiving high doses of pancreatin preparations. Hyperuricaemia and hyperuricosuria may occur.
Interaction
May impair the oral absorption of folic acid when taken together; antagonises hypoglycaemic effect of acarbose.
Therapeutic Classes
- Digestive Enzyme
Indicaitons
- Pancreatic insufficiency
Precaution
Avoid high doses in patients with cystic fibrosis. Maintain adequate hydration. Some products contain pork protein. Inactivated by heat; do not mix with hot food or liquids. May irritate oral mucosa; should not be held in mouth. Pregnancy and lactation.
Mode of Action
Pancreatin are pancreatic enzymes which hydrolyse fats to glycerol and fatty acids, break down protein into peptides, proteoses and derived substances, and convert starch into dextrins and sugars.