|Company||Libra Pharmaceuticls Ltd.|
|Active Ingredient||Dextrose 10% + Sodium Chloride 0.225%|
The dose is dependent upon the age, weight and clinical condition of the patient.
As reported in the literature, the dosage and constant infusion rate of intravenous dextrose must be selected with caution in pediatric patients, particularly neonates and low birth weight infants, because of the increased risk of hyperglycemia/hypoglycemia.
Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit.
Alternative Brands to ADS-10
Dehydration, Fluid and Electrolytes imbalance
Reactions which may occur because of the solution or the technique of administration include febrile response, infection at the site of injection, venous thrombosis or phlebitis extending from the site of injection, extravasation and hypervolemia.
If an adverse reaction does occur, discontinue the infusion, evaluate the patient, institute appropriate therapeutic countermeasures and save the remainder of the fluid for examination if deemed necessary.
- Intravenous fluid preparations
- Fluid and electrolyte imbalance
Clinical evaluation and periodic laboratory determinations are necessary to monitor changes in fluid balance, electrolyte concentrations and acid-base balance during prolonged parenteral therapy or whenever the condition of the patient warrants such evaluation.
Solutions containing dextrose should be used with caution in patients with known subclinical or overt diabetes mellitus.
Caution must be exercised in the administration of parenteral fluids, especially those containing sodium ions to patients receiving corticosteroids or corticotropin.
Do not administer unless solution is clear and container is undamaged. Discard unused portion.
Mode of Action
Dextrose and sodium chloride solutions are used as sources of electrolytes, calories and water for hydration. Sodium and chloride ions are responsible for regulating the acid-base balance of the body. Dextrose is a source of calories. It is readily metabolised and helps to decrease losses of body protein and nitrogen. It also promotes glycogen deposition and decreases or prevents ketosis.