AFM Plus
| Company | Aristopharma Limited | |
|---|---|---|
| Active Ingredient |  Fluorometholone 0.1% + Gentamicin 0.3% Eye prep | |
| Variants |
| |
Dose
Sterile Ophthalmic Suspension:
Bacterial infection: The dosage depends on the severity of the disease. The application of 1 drop 5 times daily into the conjunctival sac of the affected eye is recommended. In severe cases the dosage can be increased up to 1 drop per hour for 1 to 2 days.
Ocular postoperative infection: 1 drop 4 times daily into the conjunctival sac for 1 week. Then a reduced application frequency is recommended for the remaining part of the treatment.
Sterile Eye Ointment:
Bacterial infection: Apply 3-4 times daily into the affected eye.
Ocular postoperative infection: To support the therapy with Ophthalmic Suspension during the night apply ointment before retiring.
Alternative Brands to AFM Plus
Indication
Allergic and inflammatory conditions of the eye
Contra Indication
Hypersensitivity to any of the components. Injuries and ulceration of the cornea. Viral infections (e.g. Herpes simplex, Vaccinia) or mycosis.
Eye tuberculosis.
Glaucoma.
Side Effect
A transient burning sensation may occur after instillation. Rare: Hypersensitivity reactions including eczema of the eyelid and puncture keratitis. Prolonged use of topical steroids may delay wound healing, increase of IOP, develop cataract and cause thinning of cornea & sclera.
Therapeutic Classes
- Ophthalmic Steroid- antibiotic combined preparations
Indicaitons
- Allergic and inflammatory conditions of the eye
- Ocular inflammation
- Eye allergy
Precaution
Steroids can mask, activate or aggravate ocular infections.
Long term treatment with steroid may enhance thinning of cornea and sclera and rarely perforation of the cornea has been reported.
In case no improvement is observed after 7-8 days of treatment, other therapeutical means should be considered.
Patients experiencing blurred vision after application of the product, particularly the ointment, should refrain from driving vehicles or operating machinery.
Contact lenses should be removed before each application.
Mode of Action
Fluorometholone suppresses the migration of polymorphonuclear leukocytes and reversal of increased capillary permeability thus decreasing inflammation.
Gentamicin is an aminoglycoside that binds to 30s and 50s ribosomal subunits of susceptible bacteria disrupting protein synthesis, thus rendering the bacterial cell membrane defective.